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Cytokine Mini-Reviews
Cellular Signaling Modules

 

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  home.gif (12503 bytes) Cytokines are small  molecules, usually proteins or glycoproteins less than 30 kDa that play an essential role in the immune response to infectious agents. They are, according to Kuby (1997), "the messengers of the immune system." In this respect, cytokines are sometimes compared to hormones as a class of molecules. However, they seem to exert their effects much more locally than hormones. They are usually secreted by T helper cells or macrophages but are sometimes produced by other types of cells as well. There are at least over 30 different cytokines that are grouped together according to which class of molecules they belong.